Most importantly, if you hobnob with any other free Autoresponder or paid services and later on if you want a switch to Aweber, it can get difficult to import your list to Aweber unless with double-op-in again! Your list needs to be approved by their import specialists.  So if you are new and starting fresh -- start with Aweber. It is strongly suggested that you watch these Video Tutorials on Aweber before you decide on anything else.
These often compact agencies or single experts are specialized in email deliverability. Making sure that the email hits the inbox. They are able to solve deliverability (email goes to spam!) problems. Think about managing on-premise or their own servers, or otherwise once there is some real concern / problems with email deliverability, blacklisting, etc.
In 2002 the European Union (EU) introduced the Directive on Privacy and Electronic Communications. Article 13 of the Directive prohibits the use of personal email addresses for marketing purposes. The Directive establishes the opt-in regime, where unsolicited emails may be sent only with prior agreement of the recipient; this does not apply to business email addresses.

Molly K. McLaughlin is a New York-based writer and editor with more than a decade of experience covering technology. She has tested and reviewed all sorts of software, mobile apps, and gadgets. Before launching her freelance business, she was an editor at PC Magazine, covering consumer electronics, followed by a stint at ConsumerSearch.com, a revie... See Full Bio
Effective email marketing campaigns are designed for all devices on which users can read their emails -- desktop, tablet, and smartphone. Email campaigns that are designed for mobile devices are especially important -- a quality known as "responsive design." In fact, 73% of companies today prioritize mobile device optimization when creating email marketing campaigns.
In addition to satisfying legal requirements, email service providers (ESPs) began to help customers establish and manage their own email marketing campaigns. The service providers supply email templates and general best practices, as well as methods for handling subscriptions and cancellations automatically. Some ESPs will provide insight and assistance with deliverability issues for major email providers. They also provide statistics pertaining to the number of messages received and opened, and whether the recipients clicked on any links within the messages.
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